Enter Patient Participants

About the trial

Ankle fracture is one of the most common musculoskeletal injuries sustained in the UK.

About the trial

Background

Every day in the UK around 170 people break an ankle.

They tell us that they have pain and physical limitations for several weeks, or sometimes months, after the injury. It can also mean that they have to take a long time off work. We know some people can have pain in their ankle as well as some functional limitations for as long as three years or even longer.

In most hospitals, simple ankle breaks are treated with a plaster cast or a walking boot. If the break is more complicated with the broken bones out of place, or if they wouldn’t stay in line when walking in a boot or plaster, an operation is performed to fix the bones in place with screws and a plate.

About the trial

Current enrolment curve

About the trial

The study team

Xavier Griffin

Chief Investigator Consultant Trauma Surgeon

Xavier is the Chief Investigator for NIHR randomised clinical trials and has also received commercially funded grants. His research interest is in clinical and cost effectiveness of musculoskeletal trauma interventions.

Dr Susan Wagland

Trial Manager

As Clinical Trials Manager in Oxford Trauma Group, Susan is responsible for day-to-day management of clinical trials. Susan works with a clinical trials administrator to deliver the FAME study.

Warren Sheehan

Research Physiotherapist

Warren is the trial trainer, visiting hospitals to instruct them in trial procedures and close contact casting techniques.

About the trial

Study recruitment sites

  • Horton General Hospital
  • John Radcliffe Hospital
  • Medway Maritime Hospital
  • Milton Keynes University Hospital NHS Foundation Trust
  • Musgrove Park Hospital, Taunton
  • Southmead Hospital, Bristol
  • St Helier Hospital, Sutton
  • St Mary's Hospital, Isle of Wight
  • The Royal London Hospital
  • Kettering General Hospital
  • Doncaster Royal Infirmary
  • James Cook University Hospital
  • Northumbria Specialist Emergency Care Hospital
  • Royal Victoria Infirmary, Newcastle
  • Southport & Ormskirk Hospital NHS Trust
  • Sunderland Royal Hospital
  • Forth Valley
  • Victoria Hospital, Fife
About the trial

Trial information

Treatment

This study will compare the two commonly used treatments for unstable ankle fractures:

Surgical intervention
Close contact casting

Personal data

We will be using information from participants and medical records in order to undertake this study, and will act as the data controller for this study.  For more information see: https://www.hra.nhs.uk/information-about-patients/

Study Sponsor

This study is sponsored by The University of Oxford.

Study Funder

This study is funded by the National Institute for Health Research (NIHR) Health Technology Assessment Programme (project reference NIHR127273).

Things to know

Surgeons throughout the UK (and the world) are uncertain about the best way to treat this injury.

Registration

ISRCTN 67007305

  • Oxford Trauma
  • University of Oxford
  • National Institute for Health Research